Related Experiment Video
Updated: Jun 3, 2026
08:45
Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes
Published on: May 10, 2022
Hematologic disease in pregnancy: the obstetrician's perspective
Nicole A Smith1, Katherine E Economy
1Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA. nasmith@partners.org
Hematology/Oncology Clinics of North America
|March 30, 2011
Summary
Women with hematologic disease face higher risks during pregnancy. Careful management and planning throughout pregnancy, labor, and delivery can ensure a healthy outcome for both mother and child.
Area of Science:
- Obstetrics and Gynecology
- Hematology
- Maternal-Fetal Medicine
Background:
- Pregnancy poses significant risks for women with pre-existing hematologic conditions.
- Hematologic diseases can lead to increased maternal and fetal morbidity and mortality.
- Specialized care is crucial for managing these high-risk pregnancies.
Purpose of the Study:
- To review management strategies for pregnant women with hematologic disease.
- To highlight key considerations during each trimester of pregnancy.
- To provide guidance on labor, delivery, and postpartum care for this patient population.
Main Methods:
- Comprehensive review of existing literature and clinical guidelines.
- Focus on trimester-specific management concerns.
- Detailed discussion of diagnostic testing and medication use during pregnancy and lactation.
Main Results:
- Careful planning and preparation enable safe management of most pregnancies in women with hematologic disease.
- Trimester-specific approaches are essential for addressing evolving maternal and fetal needs.
- Proactive management of labor, delivery, and potential obstetric complications is critical.
Conclusions:
- With meticulous planning, women with hematologic disease can achieve healthy pregnancies and deliveries.
- Understanding and addressing the unique challenges of hematologic conditions in pregnancy is paramount.
- Evidence-based guidelines for diagnostic testing and medication use support safe maternal and infant outcomes.
Related Concept Videos
01:19Rh Blood Group
The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
01:15Blood Transfusion
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
02:45Blood Transfusion and Agglutination
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
01:07Teratogenicity
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
01:27Disorders of Erythrocytes
Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
01:30Venous Thrombosis IV: Nursing Management
Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...