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Updated: Jun 3, 2026

A Rat Model of Ventricular Fibrillation and Resuscitation by Conventional Closed-chest Technique
Published on: April 26, 2015
A manually powered mechanical resuscitation device used by a single rescuer: a randomised controlled manikin study
Henrik Fischer1, Stephanie Neuhold, Bernhard Zapletal
1Department of Anaesthesia, General Intensive Care and Pain Medicine, Division of Cardio-Thoracic-Vascular Surgical Anaesthesia and Intensive Care Medicine, Medical University Vienna, Austria. henrik.fischer@meduniwien.ac.at
Purpose:
The goal of this randomized, open, controlled crossover manikin study was to compare the performance of "Animax", a manually operated hand-powered mechanical resuscitation device (MRD) to standard single rescuer basic life support (BLS).
Methods:
Following training, 80 medical students performed either standard BLS or used an MRD for 12 min in random order. We compared the quality of chest compressions (effective compressions, compression depth and rate, absolute hands-off time, hand position, decompression), and of ventilation including the number of gastric inflations. An effective compression was defined as a compression performed with correct depth, hand position and decompression.
Results:
The use of the MRD resulted in a significantly higher number of effective compressions compared to standard BLS (67 ± 34 vs. 41 ± 34%, p<0.001). In a comparison with standard BLS, the use of the MRD resulted in less absolute hands-off time (264 ± 57 vs. 79 ± 40 s, p<0.001) and in a higher minute-volume (1.86 ± 0.7 vs. 1.62 ± 0.7 l, p=0.020). However, ventilation volumes were below the 2005 ERC guidelines for both methods. Gastric inflations occurred only in 0 ± 0.1% with the MRD compared to 3 ± 7% during standard BLS (p<0.001).
Conclusion:
Single rescuer cardio-pulmonary resuscitation with the manually operated MRD was superior to standard BLS regarding chest compressions in this simulation study. The MRD delivered a higher minute-volume but did not achieve the recommended minimal volume. Further clinical studies are needed to test the MRD's safety and efficacy in patients.
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Ventilatory Modes
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...

