Related Experiment Video
Updated: Jun 3, 2026

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
Published on: January 7, 2019
[Effectiveness of cognitive-associated with behavioral therapy psychopharmacological depression. Literature review
Alessandra Minelli1, Francesco Zambello, Alberto Vaona
1IRCCS San Giovanni di Dio, Fatebenefratelli, Brescia. aminelli@fatebenefratelli.it
Aim:
The main focus is to analyze meta-analyses literature inherent the efficacy of cognitive behavioural therapy (CBT) with pharmacological therapy in the treatment of depression in adults rather than pharmacological therapy alone.
Methods:
Systematic research via PubMed, fixed subset criteria.
Results:
The methanalitic review underlie that the combination of CBT with drug therapy is significantly more effective compared to single pharmacological treatment in adult depression in terms of clinical response and symptomatic improvement. In addition the CBT improves adherence to treatment and reduces the risk of relapse.
Discussion:
Even though there is only a moderate evidence that combined therapy (pharmacological plus CBT treatment) is better than pharmacological treatment alone on depressive symptoms, the results support the important impact on NHS policies, allowing future implementation of CBT therapy in public services.
Related Concept Videos
Antidepressant Drugs: MAOIs and Other Agents
Cognitive Therapy
Drug Therapy
Antianxiety Medications
Electroconvulsive Therapy
Antidepressant Drugs: Tricyclics, SSRIs, and SNRIs
Antidepressant Drugs: Overview
