Related Experiment Video
Updated: Jun 3, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
The difference in location between traumatic cerebral microbleeds and microangiopathic microbleeds associated with
Toshio Imaizumi1, Kei Miyata, Shigeru Inamura
1Department of Neurosurgery, Kushiro City General Hospital, Hokkaido, Japan. timaizum@d9.dion.ne.jp
Background And Purpose:
Microbleeds (MBs) are low-intensity spots on gradient echo T2*-weighted MRI frequently associated with cerebral microangiopathies resulting in stroke. MBs can also be caused by cerebral axonal injuries. We compared the location of MBs associated with cerebral microangiopathies with those associated with trauma.
Methods:
T2*-weighted MRI identified traumatic MBs (t-MBs) in 23 (6 females; 38.7 ± 25.8 years old) of the 312 patients with head trauma consecutively admitted to our hospital between March 2003 and March 2009. We prospectively examined for the presence of microangiopathic MBs (m-MBs) in the 131 patients (59 females; 65.2 ± 9.2 years old) admitted consecutively for stroke (May -December 2004) as controls.
Results:
We identified a total of 145 t-MBs and 504 m-MBs. t-MBs were frequently located in the mid portion of the subcortical area of the cerebrum, above the corpus callosum in axial slices, and were absent from the basal ganglia. In contrast, m-MBs were frequently located within the basal ganglia or thalamus.
Conclusion:
There are substantial differences in locations of MB development in trauma patients in comparison to stroke patients.
Related Concept Videos
Hemorrhagic Stroke l: Introduction
Hemorrhagic Stroke ll: Pathophysiology
Stroke: Introduction and Types
Ischemic Stroke ll: Pathophysiology
Transient Ischemic Attack l: Introduction
Ischemic Stroke l: Introduction

