Related Experiment Video
Updated: Jun 3, 2026

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
Published on: September 20, 2019
The use of Omegaven in treating parenteral nutrition-associated liver disease
1Department of Pediatric Gastroenterology, Stanford University Medical Center, Lucile Packard Children's Hospital, 750 Welch Road, Palo Alto, CA 94304, USA.
Abstract:
Parenteral nutrition (PN), containing fat emulsions derived from soybean, has been implicated in the progression of PN-associated liver disease and cholestasis, particularly in infants with short bowel syndrome. Clinical use of Omegaven, a parenteral fish-oil emulsion, has been shown in recent studies to be a promising therapy to reverse liver disease and cholestasis. This review summarizes the rationale, relevant clinical investigations and future direction of Omegaven therapy for PN-dependent infants.
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