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Updated: Jun 3, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Hexanuclear self-assembled arene-ruthenium nano-prismatic cages: potential anticancer agents
Vaishali Vajpayee1, Yoon Jung Yang, Se Chan Kang
1Department of Chemistry, University of Ulsan, Ulsan 680-749, Republic of Korea.
Abstract:
Two novel nano-cage compounds, 8 and 9, were prepared by self-assembly of the ruthenium complexes 4 and 5, and the tripodal donor 1. The cytotoxicity of 8 was found to be considerably stronger than that of cisplatin. The complex 8 inhibited tumor cell proliferation by interfering into regulatory pathways of the cell cycle via apoptosis.
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