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Electroconvulsive therapy and major depression in Down's syndrome
A Lazarus1, R L Jaffe, W R Dubin
1Philadelphia Psychiatric Center, Temple University School of Medicine, PA 19131.
The Journal of Clinical Psychiatry
|October 1, 1990
Summary
Electroconvulsive therapy (ECT) is a safe and effective treatment for major depression in individuals with Down syndrome. This approach shows promise, especially for those unresponsive to antidepressant medications.
Area of Science:
- Psychiatry
- Neurology
- Genetics
Background:
- Major depression is a significant comorbidity in individuals with Down syndrome.
- Treatment-resistant depression in this population presents unique challenges.
- Limited research exists on the efficacy of electroconvulsive therapy (ECT) for Down syndrome patients with depression.