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Updated: Jun 3, 2026

Targeted Plasma Membrane Delivery of a Hydrophobic Cargo Encapsulated in a Liquid Crystal Nanoparticle Carrier
Published on: February 8, 2017
Nanocrystal technology in the delivery of poorly soluble drugs: an overview
Ramesh C Nagarwal1, Rakesh Kumar, Meenakshi Dhanawat
1Department of Pharmaceutics, Institute of Technology, Banaras Hindu University, Varanasi-221005, India.
Abstract:
Extensive attempts to overcome problems related to solubility of drugs for maximizing bioavailability at targeted sites in the body have been made. The issue of drug solubility appears to attract the continued interest of pharmaceutical manufacturers. In this context, nanocrystallization has emerged as an important tool. In the present review, the authors discuss the advantages of nanocrystallized drugs and examine the products available in the market as well as drugs in the pipeline using nanocrystal-based formulations, which are being developed by pharmaceutical companies for drug delivery.
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