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Updated: Jun 3, 2026

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Isolated Hepatic Perfusion as a Treatment for Liver Metastases of Uveal Melanoma
Published on: January 25, 2015
Isolated pancreatic metastasis from melanoma. Case report
T R Portale1, V Di Benedetto, F Mosca
1Surgical Science Department, University of Catania, Italy.
Il Giornale Di Chirurgia
|April 2, 2011
Summary
Pancreatic metastases from melanoma are rare, especially isolated ones. Surgical treatment may improve survival for isolated pancreatic melanoma metastases, though it remains controversial.
Area of Science:
- Oncology
- Surgical Oncology
- Medical Research
Background:
- Pancreatic metastases occur in approximately 40% of patients with a history of malignant neoplasia, commonly from renal cell carcinoma.
- Melanoma can metastasize to the pancreas, either as part of disseminated disease or, more rarely, as isolated metastases.
Observation:
- This report details a rare case of isolated pancreatic metastasis from melanoma.
- The patient had a history of melanotic metastasis to the inguinal lymph nodes but no evidence of a primary tumor.
Findings:
- The treatment for pancreatic metastases from melanoma is not well-defined and remains controversial.
- Surgery may offer improved long-term survival when pancreatic metastases are confined to the pancreas.
Implications:
- This case highlights the importance of considering melanoma as a potential source of isolated pancreatic metastases.
- Further research is needed to establish optimal treatment strategies for pancreatic metastases from melanoma.

