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Updated: Jun 3, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Survival and transmission of community-associated methicillin-resistant Staphylococcus aureus from fomites
Rishi Desai1, Pia S Pannaraj, Jaclyn Agopian
1Division of Pediatric Infectious Diseases, Childrens Hospital Los Angeles, CA, USA. butterfinger81@gmail.com
Background:
Transmission of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) from fomites appears to play an important role in CA-MRSA outbreaks. However, the amount and duration of transmissibility of MRSA have not been quantified.
Methods:
We assessed the survival and transmission of the CA-MRSA strain USA300-0114 from 9 fomites (razors, plastic toys, ceramic, soap, wood, vinyl, towels, bed sheets, and shoulder pads). Fomites were inoculated then briefly pressed onto sterile pigskin at 5 minutes; days 1, 2, 3, 7, and 10; and then weekly for 10 weeks. The experiment was repeated using 2 methicillin-susceptible S aureus (MSSA) and 3 health care-associated (HA) MRSA strains on select fomites.
Result:
Bacteria could be transmitted to skin from all fomites except soap. Transmissibility decreased over time but more rapidly from porous (eg, towels) than nonporous (eg, vinyl) fomites (P = .0002), with some fomites showing transmissibility for more than 8 weeks after contamination. The CA-MRSA strain was transmissible longer than the HA-MRSA strains (P < .0001) and 1 MSSA strain.
Conclusion:
CA-MRSA strains are transmissible from many fomites to skin with contaminated nonporous fomites exhibiting transmissibility many weeks after contamination. Transmissibility of HA-MRSA strains demonstrated attenuated transmissibility compared with CA-MRSA strains. Findings may have implications for CA-MRSA infection prevention.
Insights
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) can spread from various surfaces for weeks, especially nonporous ones. This research quantifies CA-MRSA transmissibility from fomites, informing infection prevention strategies.
Area of Science:
- Microbiology
- Infectious Diseases
- Epidemiology
Background:
- Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) transmission from fomites is crucial in outbreaks.
- Quantifying the duration and extent of MRSA transmissibility from contaminated surfaces is essential.
Purpose of the Study:
- To assess the survival and transmission of CA-MRSA from various fomites.
- To compare the transmissibility of CA-MRSA with health care-associated MRSA (HA-MRSA) and methicillin-susceptible S aureus (MSSA) strains.
Main Methods:
- Assessed transmission of CA-MRSA strain USA300-0114 from nine fomites (e.g., razors, toys, towels, vinyl) to pigskin over 10 weeks.
- Tested transmissibility at various time points post-contamination, including 5 minutes, days 1-10, and weekly up to 10 weeks.
- Repeated experiments with MSSA and HA-MRSA strains on select fomites.
Main Results:
- Bacteria transmitted from all fomites except soap.
- Transmissibility decreased over time, faster from porous than nonporous fomites.
- CA-MRSA showed longer transmissibility than HA-MRSA and MSSA strains, with some fomites remaining transmissible for over 8 weeks.
Conclusions:
- CA-MRSA strains remain transmissible from numerous fomites for extended periods, particularly nonporous ones.
- HA-MRSA strains exhibited reduced transmissibility compared to CA-MRSA.
- Findings highlight the importance of fomite contamination in CA-MRSA spread and inform infection control measures.
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