Related Experiment Video
Updated: Jun 3, 2026

Invasive Hemodynamic Assessment for the Right Ventricular System and Hypoxia-Induced Pulmonary Arterial Hypertension in Mice
Published on: October 24, 2019
Invasive hemodynamic assessment in heart failure
Barry A Borlaug1, David A Kass
1Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic and Foundation, Rochester, MN 55905, USA. borlaug.barry@mayo.edu
Insights
Routine cardiac catheterization measures heart function, but this review explores advanced assessments. It highlights the crucial role of invasive hemodynamics in managing heart failure.
Area of Science:
- Cardiology
- Cardiovascular Physiology
Background:
- Cardiac catheterization provides standard hemodynamic measurements like pressures and cardiac output.
- These parameters are used as surrogates for cardiac preload, afterload, and global function.
- However, these metrics represent complex interactions between the heart and its loads.
Purpose of the Study:
- To review gold standard assessments of ventricular and arterial properties.
- To correlate these advanced assessments with commonly reported parameters.
- To discuss the renewed significance of invasive hemodynamics in heart failure management.
Main Methods:
- Review of established and advanced methods for assessing cardiac and vascular properties.
- Analysis of the relationship between detailed hemodynamic assessments and routine clinical parameters.
- Discussion of the clinical utility of invasive hemodynamics in heart failure.
Main Results:
- Standard hemodynamic parameters reflect complex physiological interactions.
- Specific assessments offer deeper insights into ventricular and arterial properties.
- Invasive hemodynamics are increasingly vital for accurate heart failure assessment.
Conclusions:
- Routine cardiac catheterization data offer a simplified view of cardiac function.
- Advanced hemodynamic assessments provide a more comprehensive understanding.
- Invasive hemodynamics are essential for optimizing heart failure diagnosis and treatment.
Abstract:
Routine cardiac catheterization provides data on left heart, right heart, systemic and pulmonary arterial pressures, vascular resistances, cardiac output, and ejection fraction. These data are often then applied as markers of cardiac preload, afterload, and global function, although each of these parameters reflects more complex interactions between the heart and its internal and external loads. This article reviews more specific gold standard assessments of ventricular and arterial properties, and how these relate to the parameters reported and utilized in practice, and then discusses the re-emerging importance of invasive hemodynamics in the assessment and management of heart failure.
More Related Videos
Related Concept Videos
Heart Failure II: Pathophysiology
Cardiac Catheterization II: Right Heart Catheterization
Heart Failure V: Medical Management
Heart Failure IV: Classification and Diagnostic Evaluation
Heart Failure VI: Adjunct Therapies
Heart Failure VII: Nursing Interventions

