Enhanced plating efficiency of herpesvirus DNA on herpes simplex virus type 1 DNA-transformed cells

Partial resistance of hamster cells transformed by sheared herpes simplex virus (HSV) DNA to superinfection by intact HSV could be overcome by transfection with viral DNA's. HSV DNA plated more efficiently on HSV type 1 DNA-transformed hamster cells than on spontaneously transformed hamster or rabbit cells or on hamster cells transformed by other DNA viruses.