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Related Experiment Video

Updated: Jun 3, 2026

Atomic Absorbance Spectroscopy to Measure Intracellular Zinc Pools in Mammalian Cells
13:04

Atomic Absorbance Spectroscopy to Measure Intracellular Zinc Pools in Mammalian Cells

Published on: May 16, 2019

Does zinc absorption reflect zinc status?

Janet C King1

  • 1Children's Hospital Oakland Research Institute, Oakland, CA 94609, USA. Jking@chori.org

International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift Fur Vitamin- Und Ernahrungsforschung. Journal International De Vitaminologie Et De Nutrition
|April 5, 2011
PubMed
Summary
This summary is machine-generated.

Dietary zinc intake, not zinc status, determines zinc absorption. Higher zinc intake increases total absorption but decreases the percentage absorbed, with current intake being the main factor.

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Last Updated: Jun 3, 2026

Atomic Absorbance Spectroscopy to Measure Intracellular Zinc Pools in Mammalian Cells
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Assessing Mineral Availability in Fish Feeds using Complementary Methods Demonstrated with the Example of Zinc in Atlantic Salmon
04:54

Assessing Mineral Availability in Fish Feeds using Complementary Methods Demonstrated with the Example of Zinc in Atlantic Salmon

Published on: October 29, 2021

Area of Science:

  • Human Nutrition
  • Mineral Metabolism
  • Gastrointestinal Physiology

Background:

  • Zinc homeostasis is crucial for numerous physiological processes.
  • Unlike iron, zinc absorption regulation is not fully understood.
  • Dietary factors significantly impact zinc bioavailability.

Purpose of the Study:

  • To elucidate the primary determinants of zinc absorption.
  • To investigate the relationship between dietary zinc intake and absorption efficiency.
  • To understand the role of transporters in zinc uptake.

Main Methods:

  • Analysis of existing literature on zinc absorption mechanisms.
  • Review of studies examining the impact of dietary zinc levels.
  • Examination of data on zinc transporter function (ZIP4, ZnT1).

Main Results:

  • Zinc absorption is primarily regulated by current dietary zinc intake, not zinc status.
  • Increased dietary zinc leads to higher total absorbed zinc, but a lower absorption percentage.
  • A saturable carrier-mediated process involving ZIP4 and ZnT1 transporters facilitates zinc absorption at lower intakes.

Conclusions:

  • Current dietary zinc intake is the principal regulator of zinc absorption.
  • The gastrointestinal tract adjusts endogenous zinc losses to maintain homeostasis.
  • Further research is needed on the influence of physiological state on zinc absorption efficiency.