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The basophil activation test as a promising diagnostic tool in hypersensitivity to chironomid larvae

P Cabrera-Freitag1, M Ferrer, R Martínez

  • 1Department of Allergology and Clinical Immunology, Clínica Universidad de Navarra, Pamplona, Spain. pcabrera@unav.es

Journal of Investigational Allergology & Clinical Immunology
|April 6, 2011
PubMed
Abstract

No abstract available in PubMed .

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Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
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