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Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Published on: February 9, 2011

Infantile orbital cellulitis secondary to community-associated methicillin-resistant Staphylococcus aureus

Daisuke Kobayashi1, Laurence B Givner, R Patrick Yeatts

  • 1Department of Pediatrics, Wake Forest University School of Medicine and Brenner Children's Hospital, Winston-Salem, North Carolina, USA. dkobayas@dmc.org

Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
|April 6, 2011
PubMed

Insights

Community-associated methicillin-resistant Staphylococcus aureus (MRSA) causes invasive infections in children. This study reports two infants with MRSA-induced sepsis and orbital cellulitis, highlighting a rare but serious condition in neonates.

Area of Science:

  • Pediatric Infectious Diseases
  • Ophthalmology
  • Microbiology

Background:

  • Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is a growing concern for invasive pediatric infections.
  • Orbital cellulitis, an infection of the tissues around the eye socket, is more common in older children but can occur in younger infants.

Observation:

  • This report details two infant cases of sepsis and orbital cellulitis.
  • Both cases were definitively linked to community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infection.

Findings:

  • The study identifies CA-MRSA as a causative agent in severe invasive infections, including sepsis and orbital cellulitis, in neonates.
  • Literature review supports the occurrence of orbital cellulitis in infants, though less common than in older children.

Implications:

  • Highlights the need for increased awareness of CA-MRSA in neonatal sepsis and orbital cellulitis.
  • Suggests that early recognition and appropriate antibiotic therapy are crucial for managing these severe infections in infants.

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