Primary cutaneous anaplastic large-cell lymphoma of the eyelid

Primary cutaneous CD30+ lymphoproliferative disorders are the second most common type of primary cutaneous lymphomas. Involvement of the ocular adnexa is rare. Very few have been reported affecting the eyelid primarily. The authors present 2 patients with primary cutaneous anaplastic large-cell lymphoma involving the eyelid alone. Systemic workup excluded disease elsewhere. Both patients showed complete regression of their lesion following biopsy only and no other treatment, albeit with limited follow up. A surgically induced inflammatory or immune-mediated response could have played a role in the regression of these lesions.