Coronary artery disease in patients undergoing valve replacement at a tertiary care cardiac centre

Ayaz Hussain Shaikh1, Bashir Hanif, Khursheed Hasan

  • 1Tabba Heart Institute, Karachi.

Insights

This study found that over 31% of patients undergoing valve surgery had significant coronary artery disease (CAD). The prevalence of CAD in these patients is comparable to international findings.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Vascular Medicine

Background:

  • Coronary artery disease (CAD) is a significant comorbidity in patients requiring valve surgery.
  • Understanding the prevalence of CAD in this population is crucial for surgical planning and patient outcomes.

Purpose of the Study:

  • To determine the prevalence of significant coronary artery disease (CAD) in patients undergoing valve replacement surgery.
  • To compare CAD prevalence in patients undergoing mitral, aortic, or dual valve replacement.

Main Methods:

  • Retrospective review of 144 patients undergoing valve replacement surgery between 2006-2008.
  • All patients underwent coronary angiography.
  • Significant CAD defined as coronary stenosis of ≥50%.

Main Results:

  • Overall, 45 out of 144 patients (31.3%) had significant CAD.
  • Prevalence of CAD was 32.9% in mitral valve replacement, 31.9% in aortic valve replacement, and 25% in dual valve replacement.
  • No significant difference in CAD prevalence was observed across different valve surgery types.

Conclusions:

  • The prevalence of coronary artery disease in patients undergoing valve surgery at this center is substantial.
  • Findings suggest that CAD screening and management should be integrated into the care of patients undergoing valve surgery.
Abstract

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