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Published on: August 28, 2018
The prevalence and clinical profile of angiographic coronary ectasia
Riffat Sultana1, Nuzhat Sultana, Muhammad Ishaq
1Department of Cardiology, Karachi Institute of Heart Diseases, Karachi, Pakistan.
Insights
Coronary artery ectasia (CAE) was found in 1.5% of patients undergoing angiography. This condition often affects the LAD artery and is linked to traditional cardiovascular risk factors.
Area of Science:
- Cardiology
- Vascular Biology
- Diagnostic Imaging
Background:
- Coronary artery ectasia (CAE) is a dilation of coronary arteries.
- Understanding its prevalence and patient characteristics is crucial for cardiovascular risk assessment.
Purpose of the Study:
- To determine the incidence of Coronary Artery Ectasia (CAE) in patients undergoing coronary angiography.
- To describe the patient demographics and angiographic features of CAE.
Main Methods:
- Retrospective analysis of 5000 coronary angiograms performed between August 2006 and August 2008.
- Data collected from catheterization films and medical records, including a one-year follow-up for clinical endpoints.
Main Results:
- The incidence of CAE was 2.8% (140 patients), with pure ectasia in 1.5% (75 patients).
- The Left Anterior Descending (LAD) artery was most commonly affected (63%), followed by the Right Coronary Artery (RCA) (25%).
- Associated conditions included unstable angina (50%), non-ST elevation MI (4.2%), and ST elevation MI (3.6%).
Conclusions:
- The prevalence of CAE at this center was 1.5%, predominantly in males with dyslipidemia, hypertension, and smoking history.
- CAE was frequently associated with obstructive coronary artery disease (approx. 80%).
- The LAD artery is the most commonly affected vessel in CAE.
Objective:
To determine the incidence of Coronary Artery Ectasia (CAE) at our teaching hospital to describe the patients and angiographic characteristics.
Methods:
A retrospective analysis was conducted on all coronary angiograms performed at the catheterization laboratory of Karachi Institute of Heart Diseases, a tertiary care center, between the period of August 2006 and August 2008. A one year follow up was performed to look for primary and secondary endpoints. Data were collected from catheterization films, and medical records.
Results:
Five thousand coronary angiograms were performed during the periof of the study. A total of 140 (2.8%) angiograms showed coronary ectasia of both mixed and pure types. Pure ectasia with no coronary obstructive lesions was seen in 75 (1.5%). The left anterior descending artery (LAD) was the most commonly affected vessel (63%) followed by the right coronary artery (RCA) 25% and 10% patients had circumflex artery involvement. The primary composite endpoint showed 6 (4.2%) patients with non-ST elevation MI, 5 (3.6%) with ST elevation inferior wall myocardial infarction, 70 (50%) with unstable angina and 2 (1.4%) deaths due to pulmonary oedema. Secondary endpoints showed 50% of the patients still complaining of chest pain.
Conclusion:
Prevalence of Coronary ectasia in the population presenting to KIHD during the study period was 1.5%. Majority of patients were males, associated with dyslipidaemia, hypertension and smoking. CAE was associated with obstructive coronary artery disease in about 80% of cases. LAD was the most commonly affected vessel.
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