Related Experiment Video

Updated: Jun 3, 2026

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
05:16

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

[Associations between acute heart failure and cardiovascular outcomes]

Irena Milvidaitė1, Dalia Lukšienė, Birutė Slapikienė

  • 1Institute of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Sukilėlių 17, Kaunas, Lithuania. irena.milvidaite@kmuk.lt

Medicina (Kaunas, Lithuania)
|April 7, 2011
PubMed

Insights

Acute heart failure significantly increases the risk of chronic heart failure and cardiovascular mortality in patients with acute coronary syndrome. Early diagnosis and management are crucial for improving patient outcomes.

Area of Science:

  • Cardiology
  • Clinical Medicine
  • Public Health

Context:

  • Acute coronary syndrome (ACS) is a leading cause of cardiovascular mortality.
  • The co-occurrence of acute heart failure (AHF) in ACS patients presents significant management challenges.
  • Understanding the long-term sequelae of AHF in ACS is critical for patient care.

Purpose:

  • To investigate the association between AHF and cardiovascular mortality in ACS patients.
  • To determine the incidence of chronic heart failure (CHF) one year post-ACS.
  • To analyze the impact of AHF on cardiovascular outcomes during hospitalization and follow-up.

Summary:

  • A prospective study of 1554 ACS patients revealed AHF in 32.3% during hospitalization.
  • AHF was associated with a nearly threefold increase in CHF incidence at one year (31.4% vs. 11.6%).
  • Cardiovascular mortality was significantly higher in patients with AHF during both in-hospital (11.5% vs. 1.9%) and one-year follow-up (7.7% vs. 2.3%).

Impact:

  • Diagnosed AHF in ACS patients substantially elevates the risk of developing CHF and cardiovascular death.
  • These findings underscore the importance of early identification and aggressive management of AHF in ACS.
  • Improved management strategies for AHF in ACS could reduce long-term morbidity and mortality.
Abstract

More Related Videos

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs14:35

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs

Published on: April 17, 2021

Related Concept Videos

Heart Failure I: Introduction01:27

Heart Failure I: Introduction

Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...