Related Experiment Video

Updated: Jun 3, 2026

Isolation of Cognate RNA-protein Complexes from Cells Using Oligonucleotide-directed Elution
10:53

Isolation of Cognate RNA-protein Complexes from Cells Using Oligonucleotide-directed Elution

Published on: January 16, 2017

RNA export factor RAE1 contributes to NUP98-HOXA9-mediated leukemogenesis

Tatsuyoshi Funasaka1, Hiroshi Nakano, Yu Wu

  • 1Kanazawa University; Kanazawa, Japan.

Cell Cycle (Georgetown, Tex.)
|April 7, 2011
PubMed
Summary

The mRNA export factor RAE1 plays a crucial role in NUP98 fusion-driven acute myelogenous leukemia (AML). Targeting the RAE1-NUP98 interaction may offer a novel therapeutic strategy for aggressive leukemias.

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