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Published on: October 3, 2010
Childhood intracranial germinoma with granulomatous reaction
Gülen Gül Niflioğlu1, Mehtat Unlü, Nurullah Yüceer
1Department of Pathology, Dokuz Eylül University, Faculty of Medicine, Izmir, Turkey. drgulen@ymail.com
Abstract:
Central nervous system tumors are the second most common type of childhood cancer in Turkey. Germinomas constitute two thirds of intracranial germ cell tumors. The granulomatous inflammation occurring around germinomas can cause histological diagnostic difficulty. We present a 12-year-old girl with a diagnosis of germinoma in the corpus callosum associated with granulomatous reaction to emphasize the diagnostic challenge which may occur during stereotactic biopsy interpretation or intraoperative consultation.
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