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Posterior reversible encephalopathy syndrome in a child with cyclical vomiting and hypertension: a case report
Zakareya Gamie1, Akheel Rizwan, Frances G Balen
1Department of Paediatrics, Pontefract General Infirmary, Pontefract, UK. ugm1zg@doctors.org.uk.
Insights
Posterior reversible encephalopathy syndrome (PRES) is rare in children. This case highlights its association with cyclical vomiting and hypertension, emphasizing early radiological diagnosis for effective treatment.
Area of Science:
- Neurology
- Pediatrics
- Radiology
Background:
- Posterior reversible encephalopathy syndrome (PRES) presents with headache, nausea, vomiting, seizures, and visual disturbances.
- Characteristic radiological findings aid in PRES diagnosis within a suitable clinical context.
- Prompt diagnosis facilitates the institution of appropriate clinical therapy.
Purpose of the Study:
- To present a case of posterior reversible encephalopathy syndrome (PRES) in a pediatric patient.
- To explore the association between PRES, cyclical vomiting, and hypertension in a child.
- To discuss the diagnostic challenges and clinical recovery patterns in pediatric PRES.
Main Methods:
- A case presentation of a 10-year-old Caucasian girl diagnosed with PRES.
- Initial diagnosis of cyclical vomiting and hypertension preceded the PRES diagnosis.
- Magnetic resonance imaging (MRI) was utilized to identify radiological features.
Main Results:
- The patient was diagnosed with posterior reversible encephalopathy syndrome (PRES).
- An association was noted between PRES, cyclical vomiting, and hypertension.
- Radiological abnormalities on MRI showed resolution over time, but clinical recovery was not parallel.
Conclusions:
- Posterior reversible encephalopathy syndrome (PRES) is an uncommon pediatric disorder.
- Early recognition of radiological features is crucial for diagnosing PRES, as clinical symptoms can be nonspecific.
- This case is the first to report an association between PRES, cyclical vomiting, and hypertension, with a noted discrepancy between radiological resolution and clinical recovery.
Introduction:
Posterior reversible encephalopathy syndrome is characterized by headache, nausea and vomiting, seizures and visual disturbances. It has certain characteristic radiological features, which allow diagnosis in the appropriate clinical setting and enable appropriate clinical therapy to be instituted.
Case Presentation:
A 10-year-old Caucasian girl who was hospitalized due to recurrent vomiting was diagnosed as having posterior reversible encephalopathy syndrome after an initial diagnosis of cyclical vomiting and hypertension was made.
Conclusion:
Posterior reversible encephalopathy syndrome is a rare disorder in children. Early recognition of characteristic radiological features is key to the diagnosis as clinical symptoms may be non-specific or mimic other neurological illnesses. To the best of our knowledge this is the first case to report an association between posterior reversible encephalopathy syndrome, cyclical vomiting and hypertension. Furthermore, in this case, the resolution of the abnormalities found on magnetic resonance imaging over time did not appear to equate with clinical recovery.
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