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Updated: Jun 3, 2026
05:17
Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
Published on: February 9, 2021
Synthesis, characterization and biological evaluation of some 16E-arylidene androstane derivatives as potential
Hao Guo1, Haotian Wu, Jin Yang
1State Key Laboratory of Virology, College of Pharmacy, Wuhan University, Wuhan 430072, China.
Steroids
|April 9, 2011
Abstract:
A series of new 16E-arylidene androstane derivatives were synthesized and characterized. The new compounds were screened for their anticancer activities against the human cancer cell lines SW480, A549, HepG2 and HeLa in vitro using the MTT assay. The results of the in vitro study showed that a number of compounds have shown IC(50) values lower than 20 μM against the four cancer cell lines.
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