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Related Experiment Video

Updated: Jun 2, 2026

Quantification of Mouse Heart Left Ventricular Function, Myocardial Strain, and Hemodynamic Forces by Cardiovascular Magnetic Resonance Imaging

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CMR for Assessment of Diastolic Function.

Jos J M Westenberg¹

¹Department of Radiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.

Current Cardiovascular Imaging Reports

|April 9, 2011

Summary

Heart failure with preserved ejection fraction (HFpEF) affects half of all heart failure patients. This review compares cardiovascular magnetic resonance (CMR) and echocardiography for diagnosing diastolic dysfunction, crucial for HFpEF assessment.

Area of Science:

Cardiology
Medical Imaging
Diagnostic Techniques

Background:

Heart failure with preserved ejection fraction (HFpEF) accounts for 50% of heart failure cases.
Accurate diagnosis of HFpEF relies on identifying left ventricular diastolic dysfunction.
Echocardiography is the current standard for diastolic function assessment.

Purpose of the Study:

To review and compare cardiovascular magnetic resonance (CMR) applications for diastolic function testing.
To evaluate the role of CMR in clinical practice and research for HFpEF diagnosis.
To contrast CMR's capabilities with echocardiography in assessing diastolic dysfunction.

Main Methods:

Review of current literature on cardiovascular magnetic resonance (CMR) applications for diastolic function.

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Published on: May 24, 2021

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Comparison of CMR techniques with established echocardiography methods.

Analysis of accuracy and reproducibility data for both imaging modalities.

Main Results:

CMR offers alternative applications for evaluating diastolic function.
Some CMR applications demonstrate superior accuracy and reproducibility compared to echocardiography.
CMR can serve as a complementary tool to echocardiography in diastolic function assessment.

Conclusions:

Cardiovascular magnetic resonance (CMR) presents valuable tools for assessing diastolic dysfunction in heart failure with preserved ejection fraction (HFpEF).
CMR's potential for enhanced accuracy and reproducibility warrants further investigation for clinical integration.
The comparative review highlights CMR's complementary and potentially superior role alongside echocardiography in HFpEF diagnosis.