Related Experiment Video
Updated: Jan 20, 2026

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Extended Reality in Congenital Heart Disease: 4D Flow Visualization: A Case Series in Fontan Patients
Esther B van Dijk1, Friso M Rijnberg2, Patrick J H de Koning3
1Division of Prenatal Diagnosis and Fetal Medicine, Department of Obstetrics, Leiden University Medical Center, Leiden, the Netherlands.
Background:
Extended reality (XR), a stereoscopic three-dimensional visualization technique (3DVT), enables 3D and four-dimensional (4D) cardiac visualization and can improve spatial understanding of anatomy and hemodynamics in congenital heart disease.
Cases Summary:
Four-dimensional flow magnetic resonance imaging data from 2 Fontan patients was visualized using the HoloLens, an immersive and interactive 3DVT that allowed users to explore the 4D model and select various flow effects. Complex flow patterns-such as tornado-like coiling and helical flows-provided insights into abnormal hemodynamics.
Discussion:
Monoscopic 3DVT may hinder accurate interpretation of 4D data, especially in users with lower visual-spatial abilities (VSA). XR supports these users by making 4D data more intuitive to interpret, enabling performance comparable to those with higher VSA and thereby enhancing clinical data interpretation and decision-making.
Take-Home Message:
With interactive 3D/4D models, XR can facilitate a more intuitive and accurate interpretation of clinical data, allowing users with lower VSA to achieve performance levels comparable to those with higher VSA.
More Related Videos
06:18Mixed Reality Technology and Three-Dimensional Printing in Teaching: Heart Anatomy as an Example
Published on: April 18, 2025
07:07Author Spotlight: High-Resolution 4D Light-Sheet Imaging and Virtual Reality in Zebrafish for Single-Cell Analysis of Heart Function
Published on: January 5, 2024
Related Concept Videos
07:27Implantation of Total Artificial Heart in Congenital Heart Disease
06:18Mixed Reality Technology and Three-Dimensional Printing in Teaching: Heart Anatomy as an Example
07:074D Light-sheet Imaging of Zebrafish Cardiac Contraction
06:51Light-sheet Fluorescence Microscopy to Capture 4-Dimensional Images of the Effects of Modulating Shear Stress on the Developing Zebrafish Heart
08:28Analysis of Congenital Heart Defects in Mouse Embryos Using Qualitative and Quantitative Histological Methods
09:26Combining Augmented Reality and 3D Printing to Display Patient Models on a Smartphone