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Acute Pharyngitis01:30

Acute Pharyngitis

Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Streptococcal Pharyngitis01:27

Streptococcal Pharyngitis

Streptococcal pharyngitis, commonly known as “strep throat,” is an acute infection of the oropharyngeal tissues caused by the Gram‑positive Group A Streptococcus (Streptococcus pyogenes). Transmission occurs primarily through respiratory droplets expelled during coughing, sneezing, or talking.Mechanisms of Host Entry and Immune EvasionUpon entering the host, S. pyogenes adheres to the mucosal epithelial cells of the pharynx via surface proteins, notably lipoteichoic acid and the antiphagocytic...
Tonsillitis I: Introduction01:30

Tonsillitis I: Introduction

Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
Chronic Pharyngitis01:23

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Tonsillitis II: Management01:26

Tonsillitis II: Management

This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
Diphtheria01:28

Diphtheria

Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...

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Related Experiment Video

Updated: Jun 2, 2026

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients
05:26

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients

Published on: March 1, 2024

Sore throat.

Tim Kenealy1

  • 1Department of General Practice and Primary Health Care, University of Auckland, Auckland, New Zealand.

BMJ Clinical Evidence
|April 12, 2011
PubMed
Summary
This summary is machine-generated.

This systematic review examines interventions for acute infective sore throat, evaluating treatments like antibiotics and pain relievers to reduce symptoms and prevent complications. Evidence quality was assessed using GRADE criteria.

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Area of Science:

  • General Medicine
  • Infectious Diseases
  • Pharmacology

Background:

  • Sore throat affects 10% of primary care patients annually.
  • Bacterial (e.g., Streptococcus) and viral (e.g., rhinovirus) infections cause sore throat.
  • Clinical differentiation between bacterial and viral sore throat is challenging.

Purpose of the Study:

  • To systematically review interventions for acute infective sore throat.
  • To assess the effects of interventions on symptom reduction.
  • To evaluate interventions for preventing sore throat complications.

Main Methods:

  • Systematic review of literature up to January 2010.
  • Searched Medline, Embase, The Cochrane Library, and other databases.
  • Included harms alerts from regulatory agencies (FDA, MHRA).

Main Results:

  • Included 8 systematic reviews, RCTs, or observational studies.
  • Performed GRADE evaluation for intervention evidence quality.
  • Information on effectiveness and safety of various interventions was compiled.

Conclusions:

  • Presents information on antibiotics, corticosteroids, NSAIDs, paracetamol, and probiotics.
  • Effectiveness and safety data for sore throat interventions are summarized.
  • The review provides evidence-based insights for managing acute infective sore throat.