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A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
07:14

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery

Published on: January 18, 2018

Breast pain.

Amit Goyal1

  • 1Royal Derby Hospital, Derby, UK.

BMJ Clinical Evidence
|April 12, 2011
PubMed
Summary
This summary is machine-generated.

This systematic review evaluates treatments for breast pain, finding varied effectiveness and safety profiles for interventions like hormonal therapies and NSAIDs. Further research is needed for optimal breast pain management strategies.

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Last Updated: Jun 2, 2026

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Area of Science:

  • Medical research
  • Clinical evidence synthesis
  • Pharmacology

Background:

  • Breast pain affects 70% of women, presenting as cyclical or non-cyclical types.
  • Cyclical breast pain often recurs, while non-cyclical pain shows poor treatment response.
  • Understanding treatment effects is crucial for managing this common condition.

Purpose of the Study:

  • To systematically review the effects of various treatments for breast pain.
  • To assess the effectiveness and safety of interventions for cyclical and non-cyclical breast pain.
  • To provide evidence-based information for clinical decision-making regarding breast pain management.

Main Methods:

  • Conducted a systematic review of medical literature up to May 2010.
  • Searched major databases including Medline, Embase, and The Cochrane Library.
  • Included data from systematic reviews, randomized controlled trials (RCTs), observational studies, and regulatory safety alerts.

Main Results:

  • Identified 24 relevant systematic reviews, RCTs, and observational studies.
  • Performed GRADE evaluations to assess the quality of evidence for different interventions.
  • Synthesized information on the effectiveness and safety of numerous pharmaceutical and lifestyle interventions.

Conclusions:

  • Presents findings on interventions including antibiotics, hormonal therapies (e.g., HRT, oral contraceptives), NSAIDs, and dietary changes.
  • Highlights the need for careful consideration of effectiveness and safety for each treatment option.
  • Provides a comprehensive overview of current evidence for breast pain treatments as of May 2010.