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Published on: November 3, 2023
Insights
Recurrent nosebleeds in children are common, but treatments like antiseptic cream, petroleum jelly, and silver nitrate cautery show varying effectiveness and safety. Further research is needed for optimal management strategies.
Area of Science:
- Pediatric Otolaryngology
- Evidence-Based Medicine
Background:
- Recurrent idiopathic epistaxis affects up to 9% of children.
- Nosebleeds typically originate from the anterior nasal septum.
- Many children resolve spontaneous nosebleeds with age.
Purpose of the Study:
- To systematically review the effects of treatments for recurrent idiopathic epistaxis in children.
- To evaluate the effectiveness and safety of available interventions.
Main Methods:
- Systematic review of medical literature up to May 2010.
- Inclusion of 5 randomized controlled trials (RCTs).
- GRADE evaluation of evidence quality and inclusion of regulatory harms alerts.
Main Results:
- Evidence quality for interventions was assessed using the GRADE system.
- Data on antiseptic cream, petroleum jelly, and silver nitrate cautery were analyzed.
Conclusions:
- The review presents information on the effectiveness and safety of specific treatments.
- Findings guide clinical decision-making for pediatric recurrent epistaxis.
Introduction:
Up to 9% of children may have recurrent nosebleeds, usually originating from the anterior septum, but many grow out of the problem.
Methods And Outcomes:
We conducted a systematic review and aimed to answer the following clinical question: What are the effects of treatments for recurrent idiopathic epistaxis in children? We searched: Medline, Embase, The Cochrane Library, and other important databases up to May 2010 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
Results:
We found 5 RCTs that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.
Conclusions:
In this systematic review we present information relating to the effectiveness and safety of the following interventions: antiseptic cream, petroleum jelly, and silver nitrate cautery.
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