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Related Experiment Video

Updated: Jun 2, 2026

Cystometric and External Urethral Sphincter Measurements in Awake Rats with Implanted Catheter and Electrodes Allowing for Repeated Measurements

Cystometric and External Urethral Sphincter Measurements in Awake Rats with Implanted Catheter and Electrodes Allowing for Repeated Measurements

Published on: January 30, 2018

Nocturnal enuresis.

Darcie Kiddoo¹

¹University of Alberta, Alberta, Canada.

BMJ Clinical Evidence

|April 12, 2011

Summary

This summary is machine-generated.

This systematic review evaluates treatments for nocturnal enuresis (bedwetting). It found evidence for acupuncture, alarms, desmopressin, and tricyclic antidepressants, among others.

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Detrusor Underactivity Model in Rats by Conus Medullaris Transection

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Last Updated: Jun 2, 2026

Cystometric and External Urethral Sphincter Measurements in Awake Rats with Implanted Catheter and Electrodes Allowing for Repeated Measurements

Cystometric and External Urethral Sphincter Measurements in Awake Rats with Implanted Catheter and Electrodes Allowing for Repeated Measurements

Published on: January 30, 2018

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Published on: August 28, 2020

Area of Science:

Pediatric Urology
Sleep Medicine
Evidence-Based Medicine

Background:

Nocturnal enuresis impacts a significant percentage of children and young adults.
Spontaneous resolution occurs in 15% of affected children annually.
Treatment is generally not recommended for children under 7 years old.

Purpose of the Study:

To systematically review the effectiveness and safety of various interventions for nocturnal enuresis.
To answer the clinical question regarding the effects of interventions for symptom relief.

Main Methods:

Systematic review of 19 studies including systematic reviews, randomized controlled trials (RCTs), and observational studies.
Searched major databases (Medline, Embase, Cochrane Library) up to February 2010.
Included safety alerts from regulatory agencies like the FDA and MHRA.

Main Results:

The review identified and evaluated evidence for multiple interventions.
A GRADE evaluation was performed to assess the quality of evidence for each intervention.

Conclusions:

The review presents data on the effectiveness and safety of interventions including acupuncture, anticholinergics, desmopressin, dry bed training, enuresis alarms, hypnotherapy, and tricyclic antidepressants.
Information on specific medications like oxybutynin, tolterodine, hyoscyamine, imipramine, and desipramine is provided.