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Related Concept Videos

Hybridoma Technology01:31

Hybridoma Technology

Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
Hybridoma Selection
Commonly used fusion techniques — electroporation, polyethylene glycol...
Recombinant DNA01:09

Recombinant DNA

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Related Experiment Video

Updated: Jun 2, 2026

Scalable High Throughput Selection From Phage-displayed Synthetic Antibody Libraries
12:55

Scalable High Throughput Selection From Phage-displayed Synthetic Antibody Libraries

Published on: January 17, 2015

Recombinant antibody libraries and selection technologies.

Heyue Zhou1, Yan-Liang Zhang, Guodi Lu

  • 1Sorrento Therapeutics, Inc., 6042 Cornerstone Court West, San Diego, CA 92121, USA.

New Biotechnology
|April 12, 2011
PubMed
Summary
This summary is machine-generated.

Passive immunization, using recombinant antibody libraries, is revolutionizing medicine by enabling targeted antibody therapies for various antigens. This technology fuels the development of numerous monoclonal antibody therapeutics.

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Construction of Synthetic Phage Displayed Fab Library with Tailored Diversity

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Related Experiment Videos

Last Updated: Jun 2, 2026

Scalable High Throughput Selection From Phage-displayed Synthetic Antibody Libraries
12:55

Scalable High Throughput Selection From Phage-displayed Synthetic Antibody Libraries

Published on: January 17, 2015

Creating Highly Specific Chemically Induced Protein Dimerization Systems by Stepwise Phage Selection of a Combinatorial Single-Domain Antibody Library
10:17

Creating Highly Specific Chemically Induced Protein Dimerization Systems by Stepwise Phage Selection of a Combinatorial Single-Domain Antibody Library

Published on: January 14, 2020

Construction of Synthetic Phage Displayed Fab Library with Tailored Diversity
12:31

Construction of Synthetic Phage Displayed Fab Library with Tailored Diversity

Published on: May 1, 2018

Area of Science:

  • Biomedical Science
  • Immunology
  • Therapeutic Development

Background:

  • Active immunization represents a major biomedical advancement.
  • Passive immunization is transforming medical practice through targeted antibody therapies.
  • Recombinant antibody libraries are crucial for advancing passive immunization strategies.

Purpose of the Study:

  • To highlight the impact of passive immunization and recombinant antibody libraries in medicine.
  • To underscore the role of diverse antibody libraries in therapeutic development.

Main Methods:

  • Construction and display of various antibody libraries (naive, immune, semi-synthetic, synthetic).
  • Application of rapid screening and selection technologies.

Main Results:

  • Recombinant antibody libraries significantly contribute to the progress of passive immunization.
  • Thousands of monoclonal antibody therapeutics are currently in development, driven by these technologies.

Conclusions:

  • Passive immunization, powered by recombinant antibody libraries and advanced screening, is a key driver of modern therapeutic development.
  • The versatility of antibody libraries ensures continued innovation in treating diseases through antibody targeting.