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Related Experiment Video

Updated: Jun 2, 2026

A Microfluidic-based Hydrodynamic Trap for Single Particles
10:13

A Microfluidic-based Hydrodynamic Trap for Single Particles

Published on: January 21, 2011

A microfluidic-based hydrodynamic trap: design and implementation.

Melikhan Tanyeri1, Mikhil Ranka, Natawan Sittipolkul

  • 1Department of Chemical and Biomolecular Engineering, University of Illinois Urbana-Champaign, 600 S. Mathews Ave., Urbana, IL, USA.

Lab on a Chip
|April 12, 2011
PubMed
Summary
This summary is machine-generated.

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This study introduces a microfluidic device for precise particle trapping using fluid flow alone. This hydrodynamic trap offers a non-contact method for manipulating micro- and nanoscale particles without external forces.

Area of Science:

  • Microfluidics
  • Nanotechnology
  • Biotechnology

Background:

  • Existing particle manipulation techniques often rely on external force fields (electric, optical, magnetic, acoustic).
  • There is a need for non-contact, precise methods for controlling micro- and nanoscale particles in free-solution.

Purpose of the Study:

  • To report an integrated microfluidic device for fine-scale manipulation and confinement of micro- and nanoscale particles.
  • To demonstrate a hydrodynamic trap based on active flow control at a fluid stagnation point.

Main Methods:

  • Development of a monolithic polydimethylsiloxane (PDMS)-based microfluidic device.
  • Integration of an on-chip valve for active flow control at a stagnation point.
  • Characterization of device design parameters for precise stagnation point control.

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Cell Capture Using a Microfluidic Device
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Published on: October 1, 2007

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Last Updated: Jun 2, 2026

A Microfluidic-based Hydrodynamic Trap for Single Particles
10:13

A Microfluidic-based Hydrodynamic Trap for Single Particles

Published on: January 21, 2011

Microfluidic Pneumatic Cages: A Novel Approach for In-chip Crystal Trapping, Manipulation and Controlled Chemical Treatment
09:34

Microfluidic Pneumatic Cages: A Novel Approach for In-chip Crystal Trapping, Manipulation and Controlled Chemical Treatment

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Cell Capture Using a Microfluidic Device
29:02

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Main Results:

  • Successful trapping of single micro- and nanoscale particles in a stagnation point flow.
  • Demonstration of precise control over stagnation point position for efficient trapping.
  • Non-contact confinement of fluorescent and non-fluorescent particles for extended durations.

Conclusions:

  • The developed microfluidic device provides a novel hydrodynamic trap for particle manipulation.
  • This method offers a viable, non-contact alternative to existing force-field-based techniques.
  • The platform is suitable for fundamental studies in biology, biotechnology, and materials science.