Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cardiomyopathy IV: Restrictive Cardiomyopathy

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...

Cardiac Catheterization II: Right Heart Catheterization

Cardiac Catheterization II: Right Heart Catheterization

Right Heart Catheterization: An OverviewRight heart catheterization is an invasive diagnostic procedure that measures right-sided cardiac and pulmonary artery pressures, calculates cardiac output, and identifies intracardiac shunts. It provides detailed hemodynamic data essential for diagnosing and managing various cardiovascular conditions, such as pulmonary hypertension.Access SitesCommon access sites for right heart catheterization include the internal jugular vein in the neck region, the...

Mitral Stenosis I: Introduction

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...

Cardiac Catheterization III: Left Heart Catheterization

Cardiac Catheterization III: Left Heart Catheterization

Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Adult congenital heart disease in Greece: Preliminary data from the CHALLENGE registry.

International journal of cardiology·2017

Same author

Valve repair using biodegradable ring annuloplasty: from bench to long-term clinical results.

Heart, lung and vessels·2013

Same author

[Abdominal aortic aneurysms: diagnosis and endovascular therapy].

Revue medicale suisse·2012

Same author

[Selection and preoperative follow-up of heart transplantation candidates in the French part of Switzerland].

Revue medicale suisse·2011

Same author

Novel approach to mitral valve repair in childhood dilated cardiomyopathy.

Minerva chirurgica·2011

Same author

Complex aortic coarctation, regurgitant bicuspid aortic valve with VSD and ventricular non-compaction: a challenging combination.

The Thoracic and cardiovascular surgeon·2011

Search research articles

Related Experiment Video

Updated: Jun 2, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Published on: June 11, 2019

Primary cardiac lymphoma causing right atrial occlusion.

M Cikirikcioglu¹, V C Keil, S M Cherian

¹Department of Cardiovascular Surgery, University Hospital and Medical Faculty of Geneva, Geneva, Switzerland. mustafa.cikirikcioglu@hcuge.ch

The Thoracic and Cardiovascular Surgeon

|April 12, 2011

Summary

Primary cardiac lymphoma (PCL), a rare and aggressive diffuse large B-cell lymphoma, can present insidiously. This case highlights a massive intra-cardiac tumor with rapid growth and late-stage, mild symptoms.

More Related Videos

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation

Published on: October 11, 2024

Related Experiment Videos

Last Updated: Jun 2, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Published on: June 11, 2019

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation

Published on: October 11, 2024

Area of Science:

Cardiology
Oncology
Pathology

Background:

Primary cardiac lymphomas (PCL) are exceptionally rare neoplasms.
Diffuse large B-cell lymphoma (DLBCL) is an aggressive subtype with a poor prognosis.
Cardiac tumors can mimic other cardiovascular conditions, delaying diagnosis.

Observation:

A massive, lobulated tumor was identified, occluding the right atrium and infiltrating surrounding cardiac structures.
The patient initially presented with symptoms suggestive of chronic right heart dysfunction.
Despite surgical debulking and tricuspid annuloplasty, the patient experienced multi-organ failure.

Findings:

Pathological analysis confirmed diffuse large B-cell lymphoma with a 100% proliferation rate.
The tumor's size is among the largest reported for intra-cardiac PCL.
Aggressive tumor growth occurred with surprisingly mild symptomatology until late stages.

Implications:

This case underscores the importance of considering rare cardiac tumors in the differential diagnosis of heart dysfunction.
The aggressive nature of intra-cardiac DLBCL necessitates prompt and comprehensive management strategies.
Further research into early detection and novel therapeutic approaches for PCL is warranted.