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Updated: Jun 2, 2026
10:59
Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury
Published on: November 19, 2012
[Neuroendocrine disturbances after acquired brain damage]
I Kreitschmann-Andermahr1, G Brabant
1Neurochirurgische Klinik, Universitätsklinikum Erlangen, Erlangen. ilonka.kreitschmann@ukerlangen.de
Fortschritte Der Neurologie-Psychiatrie
|April 12, 2011
Summary
Hypopituitarism, a condition affecting the pituitary gland, is common and presents with various symptoms. This review covers its causes, symptoms, and neuroendocrine effects in adults, especially after brain injury or tumor treatment.
Area of Science:
- Neurology
- Endocrinology
- Neuroscience
Context:
- Hypopituitarism is a recognized clinical condition.
- Recent studies indicate a high frequency of central endocrine disturbances in patients with brain damage.
- These disturbances are observed following traumatic brain injury, subarachnoid hemorrhage, and treatment for childhood brain tumors.
Purpose:
- To provide an overview of hypopituitarism's clinical symptomatology and pathophysiology.
- To summarize current knowledge on neuroendocrine disturbances in adult patients with brain damage.
- To highlight the relevance for practicing neurologists.
Summary:
- This article reviews hypopituitarism, a condition with significant clinical manifestations relevant to neurologists.
- It discusses classical causes (pituitary tumors) and increasingly recognized causes like brain damage from injury, hemorrhage, or cancer treatment.
- The focus is on clinical presentation, underlying mechanisms, and neuroendocrine consequences in adults.
Impact:
- Enhances understanding of hypopituitarism beyond classical causes.
- Informs neurologists about the prevalence and management of neuroendocrine dysfunction in brain-injured patients.
- Contributes to improved patient care by recognizing and addressing secondary endocrine disorders.
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