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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

Overview
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...

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Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
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Published on: April 12, 2021

[Immunosuppression in kidney transplantation].

L Balssa1, H Bittard, F Kleinclauss

  • 1Service d'urologie et transplantation rénale, hôpital Saint-Jacques, CHU de Besançon, 2, place Saint-Jacques, 25030 Saint-Jacques, France.

Progres En Urologie : Journal De L'Association Francaise D'Urologie Et De La Societe Francaise D'Urologie
|April 13, 2011
PubMed
Summary

Recent advancements in renal transplantation have focused on novel immunosuppressive drugs. This paper details the allogenic response and reviews current immunosuppressive therapies, their combinations, and emerging trends in the field.

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Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS
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Published on: November 8, 2015

Area of Science:

  • Nephrology and Immunology
  • Transplantation Medicine

Background:

  • Significant progress in renal transplantation has been achieved.
  • New immunosuppressive drugs have become available, improving outcomes.

Purpose of the Study:

  • To describe the immunological process of allogenic response in transplantation.
  • To review current immunosuppressive drugs, their combinations, and future trends.

Main Methods:

  • Literature review of immunological processes.
  • Analysis of immunosuppressive drug classes and their associations.
  • Discussion of emerging trends in immunosuppression.

Main Results:

  • Detailed description of the allogenic immune response.
  • Categorization of various immunosuppressive agents.
  • Exploration of drug combinations and novel therapeutic strategies.

Conclusions:

  • Understanding the allogenic response is crucial for effective immunosuppression.
  • Newer immunosuppressive drugs offer improved management options.
  • Future trends focus on personalized and targeted immunosuppressive therapies.