Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Birth Control Methods01:22

Birth Control Methods

Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although vasectomy...
Ovarian Cycle01:27

Ovarian Cycle

The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle length...
Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Fertilization01:38

Fertilization

During fertilization, an egg and sperm cell fuse to create a new diploid structure. In humans, the process occurs once the egg has been released from the ovary, and travels into the fallopian tubes. The process requires several key steps: 1) sperm present in the genital tract must locate the egg; 2) once there, sperm need to release enzymes to help them burrow through the protective zona pellucida of the egg; and 3) the membranes of a single sperm cell and egg must fuse, with the sperm...
Mitral Valve Prolapse III: Nursing Management01:19

Mitral Valve Prolapse III: Nursing Management

The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
Bulimia Nervosa01:30

Bulimia Nervosa

Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Maternal hypertension with nifedipine treatment associated with a higher risk for right-sided obstructive defects of the heart: a population-based case-control study.

Heart Asia·2016
Same author

A multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24.2, 17q23 and 19q13.

Human molecular genetics·2016
Same author

A Genome-wide Association Study of Nonsyndromic Cleft Palate Identifies an Etiologic Missense Variant in GRHL3.

American journal of human genetics·2016
Same author

Birth Outcomes of Children Born to Women with Rheumatoid Arthritis.

Central European journal of public health·2016
Same author

Setting research priorities to improve global newborn health and prevent stillbirths by 2025.

Journal of global health·2015
Same author

Maternal factors in the origin of infantile hypertrophic pyloric stenosis: A population-based case-control study.

Congenital anomalies·2015
Same journal

One-year follow-up of patients with hearing impairment following traumatic brain injury.

Journal of injury & violence research·2026
Same journal

Journal of injury & violence research·2026
Same journal

Elder abuse, resilience, and health-related quality of life: evidence from a cross-sectional study among older adults in Sanandaj, Iran.

Journal of injury & violence research·2026
Same journal

Psychosocial support for survivors of violence against women: a qualitative study on provider and user perspectives in a Ugandan health facility.

Journal of injury & violence research·2025
Same journal

Evaluation of seizure incidence in hospitalized patients in Kermanshah University of Medical Sciences selected Hospitals.

Journal of injury & violence research·2025
Same journal

Falls and fractures in early childhood: anatomical and developmental factors in a southeast European primary care cohort.

Journal of injury & violence research·2025
See all related articles

Related Experiment Video

Updated: Jun 2, 2026

Auricular Point Acupressure Therapy: A Safe and Effective Treatment for Postsurgical Abortion Recovery
07:28

Auricular Point Acupressure Therapy: A Safe and Effective Treatment for Postsurgical Abortion Recovery

Published on: February 3, 2026

Attempted suicide and pregnancy.

Andrew E Czeizel1

  • 1Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary. czeizel@interware.hu

Journal of Injury & Violence Research
|April 13, 2011
PubMed
Summary
This summary is machine-generated.

This study evaluated drug effects on pregnant women attempting suicide. The self-poisoning model is effective for assessing drug teratogenicity and fetotoxicity, suggesting an international monitoring system.

More Related Videos

Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes
04:08

Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes

Published on: June 27, 2025

Related Experiment Videos

Last Updated: Jun 2, 2026

Auricular Point Acupressure Therapy: A Safe and Effective Treatment for Postsurgical Abortion Recovery
07:28

Auricular Point Acupressure Therapy: A Safe and Effective Treatment for Postsurgical Abortion Recovery

Published on: February 3, 2026

Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes
04:08

Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes

Published on: June 27, 2025

Area of Science:

  • Toxicology
  • Obstetrics & Gynecology
  • Psychiatry

Background:

  • The Budapest Monitoring System studied pregnant women attempting suicide.
  • The system aimed to evaluate drug-induced congenital abnormalities from high-dose exposures.
  • It also characterized the demographics of these women.

Purpose of the Study:

  • To assess the teratogenic and fetotoxic effects of drugs in pregnant women.
  • To characterize pregnant women who attempt suicide via self-poisoning.
  • To evaluate the self-poisoning model for teratogenicity studies.

Main Methods:

  • A toxicological inpatient clinic in Budapest monitored self-poisoned patients (1960-1993).
  • 1,044 pregnant women were identified; 19 died (1.8%).
  • Birth outcomes and child development (congenital abnormalities, cognitive-behavioral status) were assessed; siblings served as controls.

Main Results:

  • Self-poisoning pregnant women were typically young (18-20 years), 62% in first pregnancy, 55% unmarried, with lower socioeconomic status.
  • 46% smoked, 22.5% drank; depression/panic disorder was infrequent (17 women).
  • Attempts peaked in the 4th post-conceptional week/2nd month; drug doses were generally lower than in non-pregnant women. 44.4% delivered live babies.

Conclusions:

  • The self-poisoning model offers advantages for dose-response estimation in teratogenicity/fetotoxicity studies.
  • An international monitoring system for self-poisoned pregnant women is recommended for a larger database.
  • This approach aids in understanding drug safety during pregnancy.