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Protein Folding

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Updated: Jun 2, 2026

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

Synthetic foldamers.

Gilles Guichard¹, Ivan Huc

¹European Institute of Chemistry and Biology, University of Bordeaux-CNRS UMR 5248, 2 rue Escarpit, 33607 Pessac, France. g.guichard@iecb.u-bordeaux.fr

Chemical Communications (Cambridge, England)

|April 13, 2011

Summary

This summary is machine-generated.

Foldamers are synthetic molecules mimicking biopolymers. Chemical synthesis advances enable complex, protein-like structures for new applications in medicine and materials science.

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Area of Science:

Synthetic chemistry
Supramolecular chemistry
Biomaterials science

Background:

Foldamers are artificial molecular architectures inspired by biopolymers.
Recent progress involves chemical synthesis of novel foldameric structures.
These structures offer new self-organized molecular scaffolds.

Purpose of the Study:

To highlight recent developments in chemically synthesized foldamers.
To discuss the potential of these novel molecular scaffolds.
To explore applications of foldamers in various scientific fields.

Main Methods:

Chemical synthesis of foldamers.
Characterization of foldamer structures and properties.
Exploration of foldamer self-organization.

Main Results:

Development of synthetic objects with protein-like size and complexity.
Creation of foldamers lacking alpha-amino acids.
Demonstration of foldamers as versatile molecular building blocks.

Conclusions:

Foldamers represent a significant advancement in synthetic molecular design.
Chemically synthesized foldamers offer new tools for creating biologically active substances, synthetic receptors, and novel materials.
The field provides exciting perspectives for future innovations in molecular science.