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Updated: Jun 2, 2026

03:38
Aptamer-Based Target Detection Facilitated by a 3-Stage G-Quadruplex Isothermal Exponential Amplification Reaction
Published on: October 6, 2022
A label-free fluorescent turn-on enzymatic amplification assay for DNA detection using ligand-responsive G-quadruplex
Chuanqi Zhao1, Li Wu, Jinsong Ren
1Division of Biological Inorganic Chemistry, State Key Laboratory of Rare Earth Resource Utilization, Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China.
Abstract:
A facile and general label-free assay for sensitive and selective DNA detection has been developed based on enzyme amplification and ligand-responsive quadruplex formation.

