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Computed Tomography (CT) Guided Implantation of a Totally Implantable Venous Access Port (TIVAP) through Subclavian Vein

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Cardiovascular implantable device infections.

George M Viola¹, Rabih O Darouiche

¹Department of Medicine, Division of Infectious Diseases, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1460, Houston, TX, 77030, USA, GMViola@mdanderson.org.

Current Infectious Disease Reports

|April 13, 2011

Summary

This summary is machine-generated.

Cardiac device infections are a growing concern with increasing device use. This review details device-related infections, covering pathophysiology, host factors, and specific device types to improve patient outcomes.

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Area of Science:

Biomedical Engineering
Infectious Diseases
Cardiology

Background:

Cardiovascular implantable devices are increasingly used due to rising life expectancy and biotechnological advancements.
Despite medical progress, infection and mortality rates associated with these devices remain high.
Understanding cardiac device-related infections is crucial for improving patient care.

Purpose of the Study:

To review the pathophysiology and general concepts of cardiac device-related infections.
To explore the interplay between medical device characteristics, host response, and microbial virulence factors.
To provide a detailed overview of infections affecting common cardiovascular implantable devices.

Main Methods:

Literature review of pathophysiology and general concepts of cardiac device infections.
Analysis of physical, chemical, and microbiologic factors contributing to infection.
Detailed examination of infections in various cardiovascular implantable devices.

Main Results:

Cardiac device infections are multifactorial, involving device properties, host immunity, and pathogen virulence.
Specific infection patterns and challenges exist for different device types.
Elevated infection and mortality rates persist despite current medical interventions.

Conclusions:

Comprehensive understanding of cardiac device infection mechanisms is essential.
Targeted strategies addressing device materials, host factors, and microbial agents are needed.
Further research and improved clinical practices are required to reduce the burden of cardiac device infections.