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Related Experiment Video

Updated: Jun 2, 2026

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
08:41

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials

Published on: August 13, 2019

Pilot study on orthodontic space closure after guided bone regeneration.

Christoph Reichert1, Matthias Wenghöfer, Werner Götz

  • 1Department of Orthodontics, University of Bonn, Germany. c_reichert@web.de

Journal of Orofacial Orthopedics = Fortschritte Der Kieferorthopadie : Organ/Official Journal Deutsche Gesellschaft Fur Kieferorthopadie
|April 13, 2011
PubMed
Summary

Orthodontic tooth movement into extraction sockets preserved with a bone substitute is feasible. This technique shows promise for orthodontic space closure, though further research is needed to prevent gingival invaginations.

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Area of Science:

  • Oral surgery
  • Orthodontics
  • Biomaterials

Background:

  • Tooth extraction often necessitates orthodontic space closure.
  • Socket preservation aims to maintain alveolar bone volume post-extraction.
  • Evaluating bone substitutes for guided bone regeneration in orthodontics is crucial.

Observation:

  • A split-mouth study compared nanocrystalline hydroxyapatite bone substitute with control in premolar extraction sockets.
  • Orthodontic space closure was achieved using NiTi closed coil springs.
  • Photographs and X-rays documented the process and outcomes.

Findings:

  • Space closure was successful without root resorption or inflammation.
  • Gingival invaginations occurred in two control sites.

Related Experiment Videos

Last Updated: Jun 2, 2026

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
08:41

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials

Published on: August 13, 2019

  • A difference in space closure velocity was noted in one patient.

    • Implications:

    • Nanocrystalline hydroxyapatite bone substitute facilitates orthodontic tooth movement into preserved extraction sockets.
    • This approach is a viable option for orthodontic space closure.
    • Further clinical trials are warranted to optimize the technique and mitigate gingival invaginations.