New acrylamide and oxazolidin derivatives from a termite-associated Streptomyces sp
Shu Feng Bi1, Fang Li, Yong Chun Song
1Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, 210093 Nanjing, PR China.
Abstract:
Two new compounds, named 2-formylpyrrole-4-acrylamide (1) and dihydrostreptazolin (2) were isolated from the fermentation broth of BY-4, an actinomycetes residing in the gut of Odontotermes formosanus. The structures of 1 and 2 were elucidated by extensive spectral analysis (1H, 13C, 2D NMR, and HR-ESIMS). The isolated compounds were assayed for cytotoxic and antimicrobial activities.
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