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Static and dynamic autonomic response with increasing nausea perception
Lauren T LaCount1, Riccardo Barbieri, Kyungmo Park
1Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, 149 Thirteenth St., #2301, Charlestown, MA 02129, USA.
Aviation, Space, and Environmental Medicine
|April 13, 2011
Summary
Nausea perception correlates with autonomic nervous system (ANS) changes, showing increased sympathetic and decreased parasympathetic activity. Dynamic cardiovagal modulation may precede nausea intensity shifts.
Area of Science:
- Physiology
- Neuroscience
- Psychology
Background:
- Nausea is a common symptom with an urge to vomit.
- The link between autonomic nervous system (ANS) activity and nausea perception requires further clarification.
Purpose of the Study:
- To investigate the relationship between autonomic nervous system (ANS) outflow and nausea perception.
- To analyze dynamic cardiovagal modulation in response to nausea stimuli.
Main Methods:
- Utilized a nauseogenic visual stimulus (translating stripes) in 17 female subjects.
- Measured autonomic outflow: heart rate (HR), heart rate variability (HRV), skin conductance response (SCR), and respiration rate.
- Employed continuous high-frequency (HF) HRV estimation for dynamic cardiovagal modulation analysis.
Main Results:
- Heart rate and skin conductance response increased with nausea intensity.
- Increased LF/HF HRV indicated a sympathetic shift in sympathovagal balance.
- Dynamic HF HRV revealed cardiovagal modulation preceding nausea perception shifts.
Conclusions:
- Increasing nausea perception is linked to heightened sympathetic and reduced parasympathetic ANS modulation.
- Findings support previous ANS studies on nausea, incorporating perception-linked and dynamic analyses.
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