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Updated: Jun 2, 2026

Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes
Published on: February 19, 2016
Toxicity evaluation of carbon nanotubes in normal human bronchial epithelial cells
Sandeep Mittal1, Vyom Sharma, N V Srikanth Vallabani
1Nanomaterial Toxicology Group, Indian Institute of Toxicology Research (CSIR), P.O. Box 80, M. G. Marg, Lucknow 226001, India.
Abstract:
Carbon nanotubes (CNTs) are well known for their exceptional thermal, mechanical and electrical properties. For many CNT applications it is of the foremost importance to know their health hazards related to their exposure. Normal human bronchial epithelial cells (BEAS-2B) has been used for assessment the cytotoxicity of SWCNT (Diameter--1.2-1.5 nm) and DWCNT (Diameter--1.3-5 nm). Clear interference of CNTs with conventional in vitro cytotoxicity assays (MTT, NRU and LDH) dye was found which was confirmed by acellular system. However morphological changes and flow cytometry showed the characteristics of cytotoxicity. Thus our study showed that there is a need of appropriate method for the assessment of cytotoxicity of CNT.
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