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Updated: Jun 2, 2026

Preparation and Characterization of Lipophilic Doxorubicin Pro-drug Micelles
Published on: August 2, 2016
Development and characterization of doxorubicin loaded microparticles against experimental visceral leishmaniasis
Sheeshpal Sharma1, Pankaj Kumar, Anil Jaiswal
1Nanomedicine Research Centre, Department of Pharmaceutics, I.S.F College of Pharmacy, Moga 142001, India.
Abstract:
Visceral leishmaniasis (VL) is the most severe of all the forms of leishmaniasis and usually lethal if untreated. The present work aimed to develop and characterize doxorubicin loaded mannan conjugated microparticles against experimental visceral leishmaniasis for selective and targeted delivery of doxorubicin to the macrophages of liver and spleen for the effective chemotherapy of VL. Macrophage targeting using doxorubicin loaded PLGA-microparticles would certainly improve the chemotherapy with reduced side effects against VL.
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