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Updated: Jun 2, 2026
05:26
Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications
Published on: April 13, 2022
Chitosan mediated targeted drug delivery system: a review
Manish P Patel1, Ravi R Patel, Jayvadan K Patel
1Department of Pharmaceutics, Nootan Pharmacy College, Gujarat, India. raviptl_84@yahoo.co.in
Summary
Chitosan
Area of Science:
- Biomaterials Science
- Drug Delivery Systems
- Polymer Chemistry
Background:
- Chitosan's unique properties drive innovation in safe and effective drug delivery.
- Its hydroxyl and amine groups allow for versatile chemical modifications.
Purpose of the Study:
- To review target-specific drug delivery carriers based on chitosan and its derivatives.
- To explore organ-specific delivery and cancer therapy applications.
Main Methods:
- Review of literature on chitosan-based drug delivery systems.
- Analysis of chemical modifications for nanoparticle formation and prodrugs.
- Examination of mucoadhesive and absorption enhancement properties.
Main Results:
- Chitosan amphiphiles form nanoparticles for drug encapsulation and targeted delivery.
- Prodrugs can be created for targeted biological activity.
- Mucoadhesion and absorption enhancement improve bioavailability.
Conclusions:
- Chitosan derivatives offer promising platforms for targeted organ-specific drug delivery.
- Advanced strategies focus on chitosan-based carriers for cancer therapy.
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