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Updated: Jun 2, 2026

Analysis of SEC-SAXS data via EFA deconvolution and Scatter
Published on: January 28, 2021
About the σA estimate
Maria Cristina Burla1, Carmelo Giacovazzo, Annamaria Mazzone
1Department of Earth Sciences, University of Perugia, Perugia, Italy.
Abstract:
The resolution parameter σ(A) is currently used for evaluating the degree of similarity between a model and the target structure. Here, quasi-Wilson distributions are used to represent the local statistics of the normalized amplitudes both for the target and for the model structure. The study uses the joint probability distribution approach to provide (i) a description of the statistical properties of the σ(A) parameter; (ii) a deeper insight into the role, for the σ(A) estimate, of the high-order moments of the target and of the model structure-factor distributions; and (iii) new statistical formulas for estimating σ(A). The theoretical results have been checked using test proteins.
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