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Updated: Jun 2, 2026
06:10
Assessment of Cellular Oxidation using a Subcellular Compartment-Specific Redox-Sensitive Green Fluorescent Protein
Published on: June 18, 2020
A small fluorophore reporter of protein conformation and redox state
Graham J Pound1, Alexandre A Pletnev, Xiaomin Fang
1Department of Chemistry, Dartmouth College, Hanover, NH 03755, USA.
Chemical Communications (Cambridge, England)
|April 14, 2011
Abstract:
A new thiol-specific reagent introduces a small bis(methylamino)terephthalic acid fluorophore into proteins. The noninvasive probe with distinct spectroscopic properties offers many advantages for protein labeling, purification, and mechanistic work promising to serve as a powerful tool in studies of protein folding and heme redox reactions.
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