Related Experiment Video

Updated: Jun 2, 2026

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
07:44

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction

Published on: March 25, 2022

Clinical outcome after percutaneous endoscopic gastrostomy in children with malignancies

Deena M Parbhoo1, Karin Tiedemann, Anthony G Catto-Smith

  • 1Department of Gastroenterology and Clinical Nutrition, Victoria, Australia.

Pediatric Blood & Cancer
|April 14, 2011
PubMed

Insights

Percutaneous endoscopic gastrostomies (PEGs) are underutilized in pediatric oncology. This study found PEGs effectively reversed weight loss in children with cancer, with few complications leading to early removal.

Area of Science:

  • Pediatric Oncology
  • Gastroenterology
  • Surgical Procedures

Background:

  • Percutaneous endoscopic gastrostomy (PEG) is infrequently used in pediatric oncology patients.
  • Nutritional support is crucial for children undergoing cancer treatment.
  • Evaluating PEG safety and efficacy in this population is warranted.

Purpose of the Study:

  • To assess the complications and efficacy of PEG placement in pediatric oncology patients.
  • To determine the impact of PEG on nutritional status (weight gain).
  • To analyze the incidence of infectious complications and their effect on PEG retention.

Main Methods:

  • Retrospective case series analysis.
  • Inclusion of pediatric patients with malignancies requiring PEG insertion.
  • Outcome measures included wound infections and changes in weight-for-age z-scores.

Main Results:

  • Sixteen PEGs were placed in 14 pediatric patients (mean age 10.3 years).
  • Nine patients experienced 16 wound infections (3.7 episodes/1,000 days).
  • Mean weight-for-age z-score declined pre-PEG but stabilized post-placement (P < 0.001).
  • Two PEGs (12%) were removed early; infectious complications rarely necessitated early removal.

Conclusions:

  • PEG placement can effectively reverse weight loss in pediatric oncology patients.
  • While infections can occur, they typically do not lead to early PEG removal.
  • PEGs represent a viable option for nutritional support in this patient group.

Related Concept Videos

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding01:15

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube through...
Peptic Ulcer Disease V: Surgical Management and Nursing Care01:25

Peptic Ulcer Disease V: Surgical Management and Nursing Care

Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
Esophageal Perforation-II: Clinical Manifestations and Management01:28

Esophageal Perforation-II: Clinical Manifestations and Management

Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations: