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Updated: Jun 2, 2026

Evaluation of the Effectiveness of Longitudinal Incision for Endoscopic Submucosal Excavation of Gastric Subepithelial Lesions
Published on: April 28, 2026
Gastric inflammatory fibroid polyp treated by endoscopic submucosal dissection
Y Hattori1, S Kobayashi, H Takahashi
1Gastroenterology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Endoscopic submucosal dissection (ESD) successfully removed a 25 mm gastric submucosal tumor, diagnosed as an inflammatory fibroid polyp (IFP). This minimally invasive technique offers a safe and effective treatment option for gastric submucosal tumors.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Pathology
Background:
- Gastric submucosal tumors (GSTs) are a diverse group of neoplasms arising from the gastric wall.
- While many GSTs are benign, malignant potential necessitates accurate diagnosis and appropriate management.
- Endoscopic submucosal dissection (ESD) is an advanced endoscopic technique for resecting early gastrointestinal cancers and large non-neoplastic lesions.
Observation:
- A 64-year-old male presented with a gastric submucosal tumor located in the anterior wall of the gastric antrum.
- The lesion measured 25 mm in diameter and demonstrated growth.
- Endoscopic examination was performed for evaluation and management.
Findings:
- Complete resection of the gastric submucosal tumor was achieved using endoscopic submucosal dissection (ESD).
- Histopathological analysis confirmed the diagnosis of an inflammatory fibroid polyp (IFP).
- The IFP measured 25 mm, and the resection margins were clear.
Implications:
- ESD is demonstrated as a safe and effective therapeutic modality for gastric submucosal tumors, including IFPs.
- This minimally invasive approach avoids the need for formal surgical gastrectomy for selected submucosal lesions.
- Further research into ESD for various types of GSTs can refine treatment guidelines and improve patient outcomes.
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