Mesenteric Hyperperfusion Syndrome following Endovascular Treatment of Chronic Mesenteric Ischemia: A Case Report

Revascularization for chronic mesenteric ischemia is generally well tolerated, yet some patients experience acute multisystem deterioration afterward. The term reperfusion syndrome, commonly used in the context of acute ischemia, is often incorrectly applied to chronic disease.

We present a case of hyperperfusion syndrome following successful two-vessel stenting in a patient with chronic mesenteric ischemia, complicated by ascites and supported by imaging and laboratory findings. Our report also highlights new-onset thrombocytopenia as part of the clinical picture. The syndrome resolved spontaneously with supportive care.

Clinicians should remain alert to hyperperfusion phenomena in chronic cases, particularly after simultaneous two-vessel revascularization.