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Updated: Jun 2, 2026
12:23
Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
Published on: April 14, 2014
[Sudden appearance and rapide progression of bilateral visual deterioration]
1Universitäts-Augenklinik Freiburg, Freiburg im Breisgau, Deutschland. Thabo.Lapp@uniklinik-freiburg.de
Summary
This case study highlights incomplete Vogt-Koyanagi-Harada syndrome, presenting with uveitis and retinal changes. Prompt steroid treatment rapidly improved vision and reversed ocular abnormalities.
Area of Science:
- Ophthalmology
- Immunology
Background:
- Vogt-Koyanagi-Harada (VKH) syndrome is a multisystem inflammatory disorder affecting the eyes, auditory and vestibular systems, and meninges.
- Incomplete VKH syndrome presents with ocular manifestations without systemic or neurological involvement.
Observation:
- A 49-year-old patient presented with intermittent, alternating visual disturbances for two weeks.
- Best corrected visual acuity was 0.1 in both eyes.
- Fundoscopy revealed right-sided anterior uveitis and multiple blister-like retinal alterations in both eyes.
Findings:
- Spectral domain optical coherence tomography (SD-OCT) confirmed multiple intraretinal cysts and neurosensory detachments.
- Histopathological correlation of these findings is discussed.
- The patient's condition was diagnosed as incomplete Vogt-Koyanagi-Harada syndrome.
Implications:
- Early diagnosis and treatment of incomplete VKH syndrome are crucial for visual recovery.
- Topical and systemic steroid therapy demonstrated rapid efficacy in reducing inflammatory symptoms.
- SD-OCT is a valuable tool for monitoring disease activity and treatment response in VKH syndrome.
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